Prospective study: evaluation of the efficacy and longevity of cross-linked hyaluronic acid in filling nasolabial folds

Prospective study: evaluation of the efficacy and longevity of cross-linked hyaluronic acid in filling nasolabial folds

Introduction: The choice of minimally invasive methods positions hyaluronic acid (HA) fillers as a leading facial rejuvenation technique. Injectable HA fillers have been widely used in the clinical treatment of facial wrinkles. However, additional information and clinical evidence on the longevity of HA filler after injection is limited. Objectives: demonstrate the efficacy, safety and longevity of cross-linked HA (AHR) 30 mg/ml (Estrianon Hyaluronic Implant 30® Allanmar International Company S.R.L., Argentina) for filling nasolabial folds (SNL). Design: multicenter, prospective, controlled clinical trial of 12 months duration. Materials and methods: 160 patients were included (132 women and 28 men, divided into cohorts of 30, 30 and 100 each) and an injectable gel of AHR 30 mg/ml was applied in the correction of SNL to evaluate safety. , effectiveness and longevity of the product. Results: a relevant correction of the depression in the sulci was observed that was maintained until the end of the study. The mean level of improvement was clinically significant in 94% of cases. The severity of NLS was reduced by approximately 2 points to the range of mild or barely noticeable. Conclusions: Estrianon Hyaluronic Implant 30® proved to be a safe, effective filler with considerable longevity. At 12 months, significant correction was still observed and the treatment was well tolerated by patients.

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12/12/2023

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