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                <text>Why aren't all continuous glucose monitoring (CGM) systems the same?</text>
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                <text>The FDA has developed a classification for CGM systems that divides them into those that require (complementary) or do not (non-complementary) the use of test strips for safe decision making.</text>
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                <text>1. Campbell F. Outcomes of using flash glucose monitoring technology by children and young people with type 1 diabetes in a single arm study. Pediatric Diabetes 2018; 19(7):1294-1301. doi: 10.1111/pedi.12735.</text>
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                <text>Novo Nordisk presentará en Argentina su nuevo tratamiento para la obesidad, Wegovy® (semaglutida 2,4 mg), durante el encuentro virtual “Wegovy®: redefiniendo la historia de la obesidad”, que se realizará el 14 de octubre de 2025 a las 19 h.</text>
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                <text>Dra. Mónica Katz, médica especialista en Nutrición, Directora de la Diplomatura en Obesidad de la Universidad Favaloro y referente nacional en obesidad y nutrición clínica.&#13;
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&#13;
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&#13;
III. Guerci B, et al. Important decrease in hospitalizations for acute diabetes events following FreeStyle Libre system initiation in people with type 2 diabetes on basal insulin therapy in France. Diabetes Technol Ther 2023 Jan;25(1):20-30.&#13;
&#13;
IV. Miller E, et al. FreeStyle Libre improves HbA1c in people receiving GLP-1 therapy for type 2 diabetes. ATTD Conference, March 6-9, 2024, Florence, Italy.&#13;
&#13;
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&#13;
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                <text>At the 17th International Conference of ATTD 2024, the central topics were the diagnosis of type 1 diabetes in preclinical stages and the contributions of technology in type 2 diabetes. In addition, the role of artificial intelligence in new monitoring options.</text>
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                <text>I. Carlson AL, et al. Flash glucose monitoring in type 2 patients managed with basal insulin in USA. BMJ Open Diabetes Res Care 2022;10(1):e002590.&#13;
&#13;
II. Guerci B, et al. Important decrease in hospitalizations for acute diabetes events following FreeStyle Libre system initiation in people with type 2 diabetes on basal insulin therapy in France. Diabetes Technol Ther 2023 Jan;25(1):20-30.&#13;
&#13;
III. Miller E, et al. FreeStyle Libre improves HbA1c in people receiving GLP-1 therapy for type 2 diabetes. ATTD Conference, March 6-9, 2024, Florence, Italy.&#13;
&#13;
IV.  Wright E, et al. Initiating GLP-1 therapy in combination with FreeStyle Libre provides greater benefit compared to GLP-1 alone. ATTD Conference, March 6-9, 2024, Florence, Italy.&#13;
&#13;
V. Choe HG, et al. Effects of patient-driven lifestyle modification using intermittently scanned continuous glucose monitoring in patients with type 2 diabetes. Results from the randomized open-label PDF study. Diabetes Care 2022;45(10):2224-2230.</text>
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                <text>&lt;strong&gt;Introduction&lt;/strong&gt;: facial aging causes cellular and anatomical changes, resulting in loss of soft tissue volume. Due to aesthetic demand, hyaluronic acid is a very good option for filling facial folds and wrinkles. &lt;strong&gt;Objectives&lt;/strong&gt;: verify the effectiveness and safety of the application of cross-linked hyaluronic acid (CLHA) for filling nasolabial folds and its permanence over time. &lt;strong&gt;Design&lt;/strong&gt;: observational and descriptive clinical, longitudinal and prospective, 12 months long. Materials and methods: a total of 100 patients (86 women and 14 men) with moderate to severe nasolabial folds were studied between July 2018 and December 2019. CLHA 30 mg/ml was used for facial filler (Estrianon Hyaluronic Implant 30®, Allanmar International Company S.R.L., Argentina) &lt;strong&gt;Results&lt;/strong&gt;: the adverse effects subsided within 7 days in 97% of the patients and in the rest of the patients within 14 days. The initial application was up to 1 ml per groove in the most severe cases. Regarding its effectiveness as a filler, its average duration was found to be up to 8 months with the corresponding reapplications. &lt;strong&gt;Conclusions&lt;/strong&gt;: Estrianon Hyaluronic Implant 30® is a safe product, its duration depends largely on the age of the patient, their habits and the condition of their skin, exceeding 8 months and up to a year.</text>
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                <text>I. Scardovi S, Goglian A, Gendra P, Gendra C. Clinical study of the efficacy, duration and adverse effects of hyaluronic acid implants in the oral-maxillofacial área. Odontoestomatol 2017;19(30):78-91. doi: 10.22592/ o2017n30a9.&#13;
II. Trévidic P, Kaufman-Janette J, Weinkle S, Wu R, Dhillon B, Antunes S, Macé E, Maffert P. Injection guidelines for treating midface volume deficiency with hyaluronic acid fillers: The ATP Approach (Anatomy, Techniques, Products). Aesthet Surg J 2022 Aug 1;42(8):920-934. doi: 10.1093/asj/sjac007.&#13;
III. Faivre J, Gallet M, Tremblais E, Trévidic P, Bourdon F. Advanced concepts in rheology for the evaluation of hyaluronic acid-based soft tissue fillers. Dermatol Surg. 2021 May 1;47(5):e159-e167. doi: 10.1097/ DSS.0000000000002916.&#13;
IV. Cifuentes-Mimoso T, Signes-Soler F. Estudio de efectos adversos tras tratamiento con implantes cutáneos de ácido hialurónico. Universitat Autonoma de Barcelona. Disponible en: https://semcc.com/master/ files/Hialuronico%20y%20efectos%20adversos%20-%20 Dras.%20Cifuentes%20y%20Signes.pdf.&#13;
V. Snibson GR, Greaves JL, Soper ND, Prydal JI, Wilson CG, Bron AJ. Precorneal residence times of sodium hyaluronate solutions studied by quantitative gamma scintigraphy. Eye (Lond) 1990;4 (Pt 4):594-602. doi: 10.1038/eye.1990.83.&#13;
VI. Sourdille P, Santiago PY, Villain F, Yamamichi M, Tahi H, Parel JM, Ducournau Y. Reticulated hyaluronic acid implant in nonperforating trabecular surgery. J Cataract Refract Surg 1999 Mar;25(3):332-9. doi: 10.1016/s08863350(99)80080-7.&#13;
VII. He Z, Han S, Zhen Z, Ding X, Liang S. The clinical use of sodium hyaluronate eyedrops as a substitute for tears. Yan Ke Xue Bao 1990 Dec;6(3-4):111-2.&#13;
VIII. Petrella RJ, DiSilvestro MD, Hildebrand C. Effects of hyaluronate sodium on pain and physical functioning in osteoarthritis of the knee: a randomized, doubleblind, placebo-controlled clinical trial. Arch Intern Med 2002 Feb 11;162(3):292-8. doi: 10.1001/archinte.162.3.292.&#13;
IX. Raynauld JP, Torrance GW, Band PA, Goldsmith CH, Tugwell P, Walker V, Schultz M, Bellamy N; Canadian Knee OA Study Group. A prospective, randomized, pragmatic, health outcomes trial evaluating the incorporation of hylan G-F 20 into the treatment paradigm for patients with knee osteoarthritis (Part 1 of 2): clinical results. Osteoarthritis Cartilage 2002 Jul;10(7):506-17. doi: 10.1053/joca.2002.0798.&#13;
X. Tamer TM. Hyaluronan and synovial joint: function, distribution and healing. Interdiscip Toxicol 2013 Sep;6(3):111-25. doi: 10.2478/intox-2013-0019.&#13;
XI. Altman RD, Moskowitz R. Intraarticular sodium hyaluronate (Hyalgan) in the treatment of patients with osteoarthritis of the knee: a randomized clinical trial. Hyalgan Study Group. J Rheumatol 1998 Nov;25(11):220312. Erratum in: J Rheumatol 1999 May;26(5):1216.&#13;
XII. Bogdan-Allemann I, Baumann L. Hyaluronic acid gel (Juvéderm) preparations in the treatment of facial wrinkles and folds. Clin Interv Aging 2008;3(4):629-34. doi: 10.2147/cia.s3118.&#13;
XIII. Jordan DR. Delayed inflammatory reaction to hyaluronic acid (Restylane). Ophthalmic Plast Reconstr Surg. 2005 Sep;21(5):401-2. doi: 10.1097/01.iop.0000173194.18050.b8.&#13;
XIV. Ågerup B, Wik O. The MonographnashaTM. 2008. Disponible en: https://docplayer.net/20739410-Nashathe-monograph-1.html.&#13;
XV. Cornejo P, Alcolea JM, Trelles MA. Perspectivas en el uso de materiales de relleno inyectables para tejidos blandos, desde nuestra experiencia. 1º parte. Cir Plást Iberolatinoam 2011;37(4):393-402.&#13;
XVI. Smith SR, Jones D, Thomas JA, Murphy DK, Beddingfield FC. Duration of wrinkle correction following repeat treatment with Juvéderm hyaluronic acid fillers. Arch Dermatol Res 2010 Dec;302(10):757-62. doi: 10.1007/ s00403-010-1086-8.&#13;
XVII. Monheit G, Beer K, Hardas B, Grimes PE, Weichman BM, Lin V, Murphy DK. Safety and effectiveness of the hyaluronic acid dermal filler VYC-17.5L for nasolabial folds. Results of a randomized, controlled study. Dermatol Surg 2018 May;44(5):670-678. doi: 10.1097/ DSS.0000000000001529.&#13;
XVIII. Galderma. Instrucciones de uso. Disponible en: https:// www.galderma.com/us/sites/default/files/2018-11/ Restylane_IFU.pdf.&#13;
XIX. Allergan. Instrucciones de uso. Disponible en https:// www.rxabbvie.com/pdf/juvederm-ultra-plus-xc_dfu.pdf.&#13;
XX. Day DJ, Littler CM, Swift RW, Gottlieb S. The Wrinkle Severity Rating Scale: a validation study. Am J Clin Dermatol 2004;5(1):49-52. doi: 10.2165/00128071200405010-00007.&#13;
XXI. Savoia A, Accardo C, Vannini F, Di Pasquale B, Baldi A. Outcomes in thread lift for facial rejuvenation: a study performed with happy lift™ tevitalizing. Dermatology Ther (Heidelb) 2014;4(1):103-14.&#13;
XXII. Sharma AN, Patel BC. Laser Fitzpatrick skin type recommendations (updated 2023 Mar 6). In: StatPearls (Internet). Treasure Island (FL): StatPearls Publishing; 2023 Jan. Disponible en: https://www.ncbi.nlm.nih.gov/ books/NBK557626/.&#13;
XXIII. Pinsky MA, Thomas JA, Murphy DK, Walker PS; Juvéderm versus Zyplast Nasolabial Fold Study Group. Juvéderm injectable gel: a multicenter, double-blind, randomized study of safety and effectiveness. Aesthet Surg J. 2008 Jan-Feb;28(1):17-23. doi: 10.1016/j.asj.2007.09.005.</text>
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                <text>Legal records: Lugones® Editorial Seal. Director: Facundo Lugones. Editor: Lic. María Fernanda Cristoforetti. Owner: Editorial Biotecnológica S.R.L. Legal address: Av. Curapaligüe 202, 9° B (1406), City of Buenos Aires, Argentina. Authors of the Lugones article Editorial: Marcelo Robles. Reproduction rights: Lugones® Editorial Seal, Editorial Biotecnológica S.R.L. Total or partial reproduction of the articles is prohibited without the authorization of the author and the publisher. Work registered in the National Directorate of Copyright, Ministry of Justice and Human Rights of the Argentine Republic. Registration of Published Work-Web Page in File No.: RL-2021-41251755-APN-DNDA#MJ. Registration of Periodical Publications in File No.: RL-2023-71140630-APN-DNDA#MJ, City of Buenos Aires, Argentina.</text>
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                <text>&lt;a href="https://www.lugoneseditorial.com.ar/novedades/estudio-de-seguridad-y-eficacia-del-acido-hialuronico-reticulado-en-relleno-de-surcos-nasolabiales/"&gt;https://www.lugoneseditorial.com.ar/novedades/estudio-de-seguridad-y-eficacia-del-acido-hialuronico-reticulado-en-relleno-de-surcos-nasolabiales/&lt;/a&gt;</text>
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                <text>&lt;em&gt;Argentina, 2023&lt;/em&gt;</text>
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        <name>hyaluronic acid crosslinked</name>
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              <text>&lt;a href="https://lugoneseditorial.com.ar/dermatologia/desbridamiento-pie-diabetico/"&gt;https://lugoneseditorial.com.ar/dermatologia/desbridamiento-pie-diabetico/&lt;/a&gt;</text>
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                <text>Entrevista con la Dra. Mabel Carrió (M.N. 68739), Médica Diabetóloga, Directora del Centro Municipal de Diabetes Dr. Alberto Maggio y del Hospital de Día de Pie Diabético Malvinas Argentinas, Directora de la Diplomatura de Pie Diabético, Universidad Nacional del Nordeste (UNNE)&#13;
&#13;
La colagenasa se emplea para realizar el desbridamiento enzimático en casos de úlceras del pie diabético dado que facilita una transición adecuada entre las distintas fases de cicatrización</text>
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                <text>Entrevista con la Dra. Mabel Carrió (M.N. 68739), Médica Diabetóloga, Directora del Centro Municipal de Diabetes Dr. Alberto Maggio y del Hospital de Día de Pie Diabético Malvinas Argentinas, Directora de la Diplomatura de Pie Diabético, Universidad Nacional del Nordeste (UNNE)&#13;
&#13;
Lic. María Fernanda Cristoforetti, Editora de Lugones Editorial</text>
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                <text>Lic. María Fernanda Cristoforetti, Editora de Lugones Editorial</text>
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                <text>Iruxol - Abbott</text>
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        <name>Mabel Carrió</name>
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        <name>Úlceras del pie diabético</name>
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              <text>&lt;a href="https://lugoneseditorial.com.ar/novedades/diabetes/monitoreo-continuo-de-glucosa/"&gt;https://lugoneseditorial.com.ar/novedades/diabetes/monitoreo-continuo-de-glucosa/&lt;/a&gt;</text>
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                <text>Monitoreo continuo de glucosa: nuevo portal de diabetes</text>
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            <description>An account of the resource</description>
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                <text>En el nuevo Portal Abbott Diabetes destacados especialistas dictan cursos certificados y on demand sobre los últimos avances en monitoreo continuo de glucosa y tecnología aplicada a la diabetes. Exclusivo para profesionales de la salud.</text>
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                <text>Lic. María Fernanda Cristoforetti, Editora de Lugones Editorial</text>
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            <name>Date</name>
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                <text>16 diciembre, 2024</text>
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                <text>Abbott Diabetes</text>
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        <name>Adrián Proietti</name>
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        <name>Alejandro Dain</name>
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        <name>Florencia Siufi</name>
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        <name>FreeStyle Libre</name>
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        <name>Gabriela Rovira</name>
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        <name>Laura Kabakian</name>
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              <text>&lt;a href="https://lugoneseditorial.com.ar/novedades/dermatologia/acido-hialuronico-labios/"&gt;https://lugoneseditorial.com.ar/novedades/dermatologia/acido-hialuronico-labios/&lt;/a&gt;</text>
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                <text>Lip volumization with cross-linked hyaluronic acid 18 mg/ml. Efficacy and safety in 102 treated patients</text>
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                <text>Introduction: beauty trends have increased the demand for aesthetic procedures, especially the use of hyaluronic acid (HA), to rejuvenate the face and enhance lips. This safe and effective treatment hydrates, fills wrinkles, and restores volume to different areas of the face. HA is obtained from non-animal sources, is non-immunogenic, and possesses antioxidant properties. The perioral region, key to facial aging, is highly sought after for correcting wrinkles, folds, and the loss of definition caused by factors such as age, sun exposure, and lifestyle habits. Cross-linked hyaluronic acid (HRA) is an ideal option for restoring volume to this area.&#13;
&#13;
Objectives: to evaluate the safety, efficacy and adverse effects of using HRA 18 mg/ml as a lip filler. &#13;
&#13;
Materials and methods: a prospective clinical study included 102 patients (81 women and 21 men), aged 25–65, who required lip volumization and received Cientific Hyaluronic Facial Implant 18® (HRA 18 mg/ml). Treatment efficacy was assessed using the Global Aesthetic Improvement Scale (GAIS). Initial lip volume and perioral wrinkle severity were assessed using the photonumeric scales MERZ (Merz Lip Fullness Scale, MLFS) and Wrinkle Severity Rating Scale (WSRS), respectively. Safety was determined by analyzing local reactions at the injection site and the occurrence of adverse events. The product was administered at a dose of up to 1 ml per half of the lip in an initial application (T0), with follow-ups at 1, 3, and 8 months. If necessary, a single reapplication was performed during these follow-ups. Treatment efficacy was assessed at a final follow-up at 12 months. &#13;
&#13;
Results: adverse effects were mild, of immediate onset, common for this type of treatment, which resolved without the need for special treatment. The volumizing effect of HRA 18 mg/ml was effective in 98% of treated patients, with a gradual decrease after 12 months. A significant improvement in lip hydration and firmness was observed. &#13;
Conclusions: HRA 18 mg/ml is a safe and effective treatment as a dermal filler in lips, with high volume retention and lasting up to 12 months. Patients and professionals experienced high satisfaction, and improvements in skin firmness and elasticity were observed. The results support HRA as a viable and beneficial option in aesthetic medicine.</text>
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                <text>Claudio Dachevsky</text>
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            <name>Date</name>
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                <text>12/05/2025</text>
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                <text>Allanmar</text>
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                <text>&lt;a href="https://doi.org/10.47196/0595"&gt;https://doi.org/10.47196/0595&lt;/a&gt;</text>
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        <name>hyaluronic acid</name>
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        <name>volumization</name>
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